The role of molecular strategies in the evaluation of surgical margins in oropharyngeal squamous cell carcinoma

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Anastasios N. Kanatas (1*), Andrew T. Harris (2), Michael Messenger (3), David Houghton (4), Simon N. Rogers (5)

1 Oral and Maxillofacial Department, Leeds Dental Institute, The Worsley Building, Leeds, United Kingdom.
2 Oral Biology, University of Leeds, Leeds, .
3 Tissue Engineering Research, Department of Oral Biology, Leeds Dental Institute, Leeds, United Kingdom.
4 Oral and Facial Specialties Department, Pinderfields General Hospital, Wakefield, United Kingdom.
5 Regional Maxillofacial Unit, Faculty of Health, Edge Hill University, University Hospital Aintree, Liverpool, .
(*) Corresponding Author:
Anastasios N. Kanatas
a.kanatas@doctors.org.uk

Abstract

The recurrence of a tumour at the resection margins in head and neck squamous cell carcinoma (HNSCC) has profound implications on the morbidity and mortality of the patient. At present HNSCC does not undergo any form of molecular analysis to aid treatment strategy and prognosticate for those individuals at higher risk of recurrence. This article aims to review current research into molecular strategies for tumour evaluation, highlighting conflicting evidence and possible novel concepts for further exploration.

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How to Cite
Kanatas, A. N., Harris, A. T., Messenger, M., Houghton, D., & Rogers, S. N. (2011). The role of molecular strategies in the evaluation of surgical margins in oropharyngeal squamous cell carcinoma. Oncology Reviews, 3(3), 161-167. https://doi.org/10.4081/oncol.2009.161

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