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The role of perioperative radiotherapy in gastric cancer

Thales Paulo Batista, Lucas Marque de Mendonça, Ana Luiza Fassizoli-Fonte
  • Thales Paulo Batista
    Department of Surgery/Oncology, FPS/IMIP - Faculdade Pernambucana de Saúde, Instituto de Medicina Integral Professor Fernando Figueira, Recife/PE, Brazil | t.paulo@bol.com.br
  • Lucas Marque de Mendonça
    Department of Radiotherapy, FPS/IMIP - Faculdade Pernambucana de Saúde, Instituto de Medicina Integral Professor Fernando Figueira, Recife/PE, Brazil
  • Ana Luiza Fassizoli-Fonte
    Department of Radiotherapy, FPS/IMIP - Faculdade Pernambucana de Saúde, Instituto de Medicina Integral Professor Fernando Figueira, Recife/PE, Brazil

Abstract

Gastric cancer is one of the most common neoplasms and a main cause of cancer-related mortality worldwide. Surgery remains the mainstay for cure and is considered for all patients with potentially curable disease. However, despite the fact that surgery alone usually leads to favorable outcomes in early stage disease, late diagnosis usually means a poor prognosis. In these settings, multimodal therapy has become the established treatment for locally advanced tumors, while the high risk of locoregional relapse has favored the inclusion of radiotherapy in the comprehensive therapeutic strategy. We provide a critical, non-systematic review of gastric cancer and discuss the role of perioperative radiation therapy in its treatment.

Keywords

Stomach Cancer, Radiation Therapy, Multimodal Treatments.

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Submitted: 2012-10-17 03:17:53
Published: 2012-12-20 18:28:02
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Copyright (c) 2012 Thales Paulo Batista, Lucas Marque de Mendonça, Ana Luiza Fassizoli-Fonte

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